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Title 

CONVIRT: a web-based tool for transcriptional regulatory site identification using a conserved virtual chromosome

Authors 

Taewoo RyuS LeeCheol-Goo HurD Lee

Publisher 

Korean Society for Biochemistry and Molecular Biology

Issue Date 

2009

Citation 

BMB Reports, vol. 42, no. 12, pp. 823-828

Abstract 

Techniques for analyzing protein-DNA interactions on a genome-wide scale have recently established regulatory roles for distal enhancers. However, the large sizes of higher eukaryotic genomes have made identification of these elements difficult. Information regarding sequence conservation, exon annotation and repetitive regions can be used to reduce the size of the search region. However, previously developed resources are inadequate for consolidating such information. CONVIRT is a web resource for the identification of transcription factor binding sites and also features comparative genomics. Genomic information on ortholog-independent conserved regions, exons, repeats and sequences is integrated into the virtual chromosome, and statistically over-represented single or combinations of transcription factor binding sites are sought. CONVIRT provides regulatory network analysis for several organisms with long promoter regions and permits inter-species genome alignments. CONVIRT is freely available at http://biosoft.kaist. ac.kr/convirt.

ISSN 

1976-6696

Link 

http://dx.doi.org/10.5483/BMBRep.2009.42.12.823

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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