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Title | An iminocoumarin-based fluorescent probe for the selective detection of dual-specific protein tyrosine phosphatases |
| 이중특이성 PTP의 선택적 검출을 위한 이미노쿠마린 형광탐침 |
Authors | T I Kim; Myung Sun Jung; Sang Jeon Chung; Y Kim |
Publisher | Wiley-Blackwell |
Issue Date | 2010 |
Citation | Chemistry ？ A European Journal, vol. 16, no. 18, pp. 5297-5300 |
Keywords | Cyclization; Dual specificity; Fluorescent probes; Protein tyrosine phosphatases |
Abstract | (Figure Presented) Seeing is believing: A fluorescent probe for monitoring the activity of dual-specific protein tyrosine phosphatases (PTPs) has been developed (see scheme). Selective enzymatic hydrolysis and subsequent intramolecular cyclization results in a highly fluorescent iminocoumarin fluorophore. |
ISSN | 0947-6539 |
Link | |
Appears in Collections | |
Registered Date |
2019-05-02 |
