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Title 

An iminocoumarin-based fluorescent probe for the selective detection of dual-specific protein tyrosine phosphatases

 

이중특이성 PTP의 선택적 검출을 위한 이미노쿠마린 형광탐침

Authors 

T I KimMyung Sun JungSang Jeon ChungY Kim

Publisher 

Wiley-Blackwell

Issue Date 

2010

Citation 

Chemistry ? A European Journal, vol. 16, no. 18, pp. 5297-5300

Keywords 

CyclizationDual specificityFluorescent probesProtein tyrosine phosphatases

Abstract 

(Figure Presented) Seeing is believing: A fluorescent probe for monitoring the activity of dual-specific protein tyrosine phosphatases (PTPs) has been developed (see scheme). Selective enzymatic hydrolysis and subsequent intramolecular cyclization results in a highly fluorescent iminocoumarin fluorophore.

ISSN 

0947-6539

Link 

http://dx.doi.org/10.1002/chem.201000154

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2019-05-02


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