상세 정보

underline
Metadata Downloads : dc(xml) or Excel
Cited 0 time in scopus ci

Title 

Synthesis of benzoxazole amides as novel antifungal agents against Malassezia furfur

Authors 

B J KimJ KimYoung Kook KimS Y ChoiH Y Park Choo

Publisher 

The Korean Chemical Society

Issue Date 

2010

Citation 

Bulletin of the Korean Chemical Society, vol. 31, no. 5, pp. 1270-1274

Keywords 

AntifungalBenzoxazole amidesMalassezia furfur

Abstract 

Malassezia is a pathogenic fungus that causes skin diseases, such as tinea versicolor, atopic dermatitis and fatal sepsis. We report the synthesis of a series of benzoxazole amides and evaluation of their antifungal activity against Malassezia furfur. Twelve benzoxazole amides were prepared through the cyclization of the substituted 2-hydroxy aniline with N-(bis- methylsulfanylmethylene) amides. Among the prepared compounds, the compounds 4a, 8b, 8c and 8d showed in vitro antifungal activity.

ISSN 

0253-2964

Link 

http://dx.doi.org/10.5012/bkcs.2010.31.5.1270

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


There are no files associated with this item.
qrcode

FusionCharts.
DSpace Software Coptright(c) 2010 MIT and Hewleft-Packard  /  KRIBB-REPOSITORY ( Email:jakim@kribb.re.kr)