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Title 

New biological functions and applications of high-molecular-mass poly-gamma-glutamic acid

Authors 

Haryoung PooC ParkM S KwakD Y ChoiS P HongI H LeeY T LimY K ChoiS R BaeH UyamaC J KimM H Sung

Publisher 

Wiley-Blackwell

Issue Date 

2010

Citation 

Chemistry & Biodiversity, vol. 7, no. 6, pp. 1555-1562

Abstract 

Ultra-high-molecular-weight poly-γ-glutamic acid (γ-PGA) is a most promising biodegradable polymer that is produced by Bacillus subtilis (chungkookjang). Attractive properties of γ-PGA are that it is water soluble, anionic, biodegradable, and edible. Development of γ-PGA has pursued in terms of cosmetics/skin care, bone care, nanoparticle for drug delivery system, hydrogel, and so on. Very recently, our research has shown that γ-PGA can be used as an immune-stimulating agent, especially at high molecular weight. This review presents the synthesis and production of high-molecular-weight γ-PGA and its various applications in industrial fields.

ISSN 

1612-1872

Link 

http://dx.doi.org/10.1002/cbdv.200900283

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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