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Title 

Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2'-deoxyuridines

Authors 

S M ParkH YangSong Kyu ParkHwan Mook KimB H Kim

Publisher 

Elsevier

Issue Date 

2010

Citation 

Bioorganic & Medicinal Chemistry Letters, vol. 20, no. 19, pp. 5831-5834

Keywords 

1,3-Dipolar cycloaddition reaction2′-DeoxyuridineAnticancer activityPerfluoroalkyltriazole

Abstract 

We have focused on the C5-modification of 2′-deoxyuridine with substituted heterocycles for bioactivity, such as antiviral or anticancer activity. Herein, we report a novel class of nucleoside analogues with perfluoroalkyltriazole moiety as an anticancer drug candidate.

ISSN 

0960-894X

Link 

http://dx.doi.org/10.1016/j.bmcl.2010.07.126

Appears in Collections

1. Journal Articles > Journal Articles

Registered Date

2017-04-19


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